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Advances in Inorganic Chemistry

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DNA was diluted to 100 ng l 1 in 0.4 M NaOH and 10 mM EDTA (pH 8.0) and denatured by heating at 100 C for 10 min

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The effect of these changes is to alter the function of enzyme proteins involved in DNA repair

With metabolic acidosis (a reduction of the serum bicarbonate level), protons (acid) enter the cells and, to maintain electrical neutrality, potassium shifts from within the cells into the extracellular space