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However, overexpression of myo-inositol oxygenase (MIOX) can aggravate cisplatin-induced ferroptosis in the context of AKI by downregulating GPX4 activity, promoting lipid peroxidation and increasing the ferritinophagy rate [172]

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doi: 10.1016/j.celrep.2014.10.032 68 GrassetEPuelACharpentierJColletXChristensenJETercFet al