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The European Medicines Agency's assessment reports and the medicine's Summary of Product Characteristics do not identify colon cancer as a safety concern

Secondly, the number of events reported was very low

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Semaglutide 2.4 mg long-term clinical outcomes in patients with obesity or overweight: a real-world retrospective cohort study in the United States (SCOPE 12 months)

Quantification was conducted in QuPath software, with cell detection algorithms identifying DAPI-positive nuclei co-expressing c-Fos