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SKU: 62054428090

4.1
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Description

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Despite its therapeutic efficacy, tacrolimus has a narrow therapeutic window (520 ng/mL whole blood 1012 h post-dose) and frequently displays episodes of toxicity, such as nephrotoxicity, neurotoxicity, and glucose intolerance ( 5 nmol per 10 6 RBCs ( cistrans peptidylprolyl isomerase activity sharing the ability to bind immunosuppressive drugs ( cistrans isomerase activity, while FKBP-13 is a 13-kDa membrane-associated protein with 43% amino acid identity with FKBP12 ( Another class of immunosuppressant is represented by the serine/threonine kinase inhibitor

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