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Whilst prednisolone and Wegovy do not interact directly at a pharmacological level, several important clinical considerations emerge when these medications are used together, primarily relating to their contrasting metabolic effects

c ) Baseline BMI with placebo-adjusted weight change

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REWIND demonstrated a 12% reduction in three-point MACE (cardiovascular death, nonfatal myocardial infarction, or nonfatal stroke), with a hazard ratio of 0.88 (95% CI 0.79-0.99)