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347 Activated TGF- binds to its transmembrane receptor (TR), subsequently inducing the phosphorylation of suppressor of mothers against decapentaplegic (SMAD) and its translocation into the nucleus, which suppresses hepatocyte proliferation by inhibiting the expression of downstream DNA synthesis-related genes

The accumulation of lipid peroxides leads to oxidative damage of cell membranes, disrupting their structural and functional integrity, and serves as an important initiating step in promoting ICD

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Reconstitution Steps Pull the chosen volume of bacteriostatic water ( 2.0 mL for 2.5 mg/mL, or 1.0 mL for 5 mg/mL) into a sterile syringe

Performed the experiments: MS AK DD AZS

Reconstituted Dry powder is inherently more stable since degradation reactions require a solvent medium