The base effect: why expected widening amplifies the signal A third of the savings made on food by users of GLP-1 medications are being redirected to other health and wellness categories (clothing, wellness products), according to analysts cited by LinkedIn
Preclinical studies in rodents have shown an association between GLP-1 receptor activation and thyroid C-cell changes, although a direct causal link in humans has not been established, and UK/EU SmPCs for authorised GLP-1 RAs do not list MTC or MEN2 as a formal contraindication
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Fineman MS, Koda JE, Shen LZ et al (2002) The human amylin analog, pramlintide, corrects postprandial hyperglucagonemia in patients with type 1 diabetes
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GLP-1 medications create the conditions for change, but lasting success depends on adopting healthier habits