There is no established evidence that semaglutide directly impairs fertility in men or women
Its usually worst during dose escalation and tends to improve as your body adapts
Each health condition you have be it heart disease, kidney issues, or anything else can influence how your body responds to this medication
A prespecified analysis of the SELECT trial examined the relationship between changes in adiposity measures (body weight and waist circumference) and cardiovascular outcomes among 17,604 patients with obesity or overweight and established cardiovascular disease but without diabetes.[1] The analysis revealed that cardiovascular outcomes were similar among semaglutide-treated patients who did or did not lose at least 5% of their baseline body weight, and that semaglutide consistently reduced major adverse cardiovascular events across the full spectrum of baseline body mass index values
Another goal of the study was weight loss, and the drug succeeded there, too: Participants on semaglutide lost about 13% of their body weight, compared with 2.6% for those on placebo, over the course of the year-long trial
Consider the use of antidepressants for people living with depression