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Kiani MT, Higgins CA, Almquist BD

Stimulation of GHS-R1a leads to a dose-dependent increase in circulating GH and IGF-1 levels, promoting anabolic tissue responses. Nagaya , Circulation Research Additionally, GHRP-6 strongly activates ghrelin pathways , which can result in significant appetite stimulation a unique feature that makes it particularly useful during bulking or recovery from injury

Des-acyl ghrelin overexpression in transgenic mice causes a decrease in body weight, food intake, fat pad mass weight, and decreased linear growth compared to normal littermates (356)

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