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Additionally, Ozempic and Wegovy are approved to treat heart disease in people with established heart disease who also have type 2 diabetes (Ozempic) or excess weight (Wegovy)

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Leg cramps are not listed as a recognized adverse effect in the official FDA prescribing information for semaglutide products

Accessed October 15, 2025

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These mechanisms not only support glycaemic control and metabolic improvements but also contribute to weight loss by increasing satiety, reducing appetite and food cravings, lowering the preference for high-fat and energy-dense foods, and improving overall eating behaviour (Fig