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As of 2025, there are no FDA-approved therapies specifically indicated for CHE in the United States, and existing treatments lack broad immunologic specificity to address the complex inflammatory landscape of the condition

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[DOI] [PubMed] [PMC] Mndez-Lara KA, Rodrguez-Milln E, Sebastin D, Blanco-Soto R, Camacho M, Nan MN, et al

The coumaric acid and syringic acid ameliorate acetic acid-induced ulcerative colitis in rats via modulator of Nrf2/HO-1 and pro-inflammatory cytokines

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Furthermore, our previous research has demonstrated the functional significance of elevated striatal DA