This broad expression spectrum increases the risk of off-target accumulation, which may exacerbate GLP-1RA-associated side effects including nausea, delayed gastric emptying, tachycardia, and arrhythmias
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Abstract Background The potential benefits and risks of combination therapy with sodium-glucose co-transporter-2 inhibitors (SGLT-2is) and glucagon-like peptide-1 receptor agonists (GLP-1RAs) versus monotherapy remain a subject of debate to optimize metabolic and cardiovascular outcomes in patients with type 2 diabetes mellitus
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Estos pueden ser signos de infeccin o reaccin alrgica local que requieren evaluacin mdica