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10.1056/NEJMra1603471 N

PMID: 16901595

Human multipotent adipose-derived stem cells differentiate into functional brown adipocytes

They also profoundly influence the behavior of other cells within the joint, particularly the activation state of immune cells like FLS and infiltrating macrophages, by modulating signals such as lipid peroxidation products and debris released from dying cells

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Jumping to the maintenance dose immediately leads to significant gastrointestinal side effects that can derail an entire protocol