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Las investigaciones han demostrado que estos genes pueden ser activados a travs de vas de sealizacin celular, siendo Nrf2 la ms importante

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MTEP, a selective mGluR5 antagonist, had a neuroprotective effect but did not prevent the development of spontaneous recurrent seizures and behavioral comorbidities in the rat lithiumpilocarpine model of epilepsy

However, complete discontinuation typically results in weight regain, making CagriSema a long-term commitment requiring indefinite maintenance dosing

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