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Compared with control mice, GSH-depleted mice exhibited similar body weight gain (Supplemental Figure 2A) and food intake (Supplemental Figure 2B), a mild increase of carbon dioxide production (Supplemental Figure 2C), and similar RER (Supplemental Figure 2D) and locomotor activity (Supplemental Figure 2E)

the number of epidermal melanocytes is normal or only slightly increased

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