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Gluten and casein-derived molecules, if present in subjects with altered immune system, like in ASD, can cross the highly permeable intestinal barrier, and activate pro-inflammatory processes, releasing pro-inflammatory mediators that travel to the brain centers through the blood, contributing to neuro-inflammatory activities ( 5 Antioxidants targeting oxidative stress and neuroinflammation in ASD Besides excessive levels of oxidative stress and pro-inflammatory molecules, ASD patients are also distinguished for their nutritional deficits

Competing interests The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper