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The $36 average monthly PDP premium is more than 4 times higher than the $8 average monthly premium for drug coverage in MA-PDs (weighted by enrollment) (Figure 4)

Healthy people have relatively low GLP-1 concentrations in general, but a high amount of variability over the course of the day

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To overcome this obstacle, GLP-1 receptor agonists that have increased resistance to DPP-4 (such as exenatide and liraglutide) or DPP-4 inhibitors (such as sitagliptin, vildagliptin, saxagliptin, alogliptin, and linagliptin) have been used in animal and human studies [6,7]

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However, pregnancy and certain health conditions may cause increased excretion of carnitine, which could increase risk of deficiency