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Medical management of anticoagulation takes priority

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IGF-1 LR3 and CJC-1295 both ultimately converge on skeletal muscle anabolism, yet their pharmacological mechanisms are fundamentally different: IGF-1 LR3 acts as a direct, long-acting IGF-1 receptor agonist that bypasses the hypothalamic-pituitary axis entirely, while CJC-1295 is a GHRH analogue that stimulates endogenous GH pulses from the pituitary, which then drives hepatic IGF-1 synthesis over hours