Clinical trials show slightly lower rates of gastrointestinal side effects with Ozempic compared to Mounjaro, though both cause similar issues
This should be integrated as part of a holistic, multifactorial approach to type 2 diabetes that includes weight, blood pressure and lipid management (Fig
doi: 10.1016/j.drudis.2016.01.013 12 AugestadI
By concurrently modulating metabolic dysfunction and inflammatory signaling, GLP-1RAs could potentially reduce the required doses of biologics or other immunosuppressive therapies, thereby minimizing treatment-related toxicity while improving overall disease control
This approach provides flexibility in food choices while maintaining blood glucose control
For sustained results, semaglutide likely needs to be continued long-term, and healthy diet and exercise remain critical to maintain weight loss