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Weeks 6-8: Peak Effect Window What's happening internally: Maximum fat oxidation response

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In a CLP-induced mouse model of AKI, the E3 ligase MDM2 increased the expression of LMNB1 by promoting the ubiquitinated degradation of p53.LMNB1 may promote mitochondrial damage and ferroptosis in renal tubular epithelial cells and be involved in the development of AKI[22]

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Moreover, phospholipase C (PLC) activity in the hippocampal neurons was also elevated by BHBA (Figure 3B)

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