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[DOI] [PMC free article] [PubMed] [Google Scholar] Listenberger LL, Han X, Lewis SE, Cases S, Farese RV, Ory DS, et al

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La mise en vidence dune majoration de la scrtion dinsuline aprs ladministration de glucose par voie orale par rapport son administration intraveineuse, connue sous le nom deffet incrtine , a t suivie de la dcouverte des deux principales hormones intestinales responsables de cet effet : le GIP ( glucose-dependent insulinotropic polypeptide ) et le GLP-1 ( glucagon-like peptide-1 )

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