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In another trial, semaglutide demonstrated a 26 percent reduction in major adverse cardiovascular events in patients with type 2 diabetes at high cardiovascular risk

Most GLP-1-related headaches can be effectively managed with simple interventions

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In 2024, the ESC guidelines for elevated blood pressure and hypertension classified GLP-1 RA as therapies that have shown blood pressure-lowering properties but are awaiting further supportive evidence from cardiovascular outcomes trials prior to guideline endorsement and routine use in hypertension [49]

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