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It has been suggested that c-MET leads to the induction of genes that are actively involved in invasion and metastasis
However, preliminary tumor tissue analysis showed downregulation of 12 cell cycle-related genes and nine apoptosis-related genes in the treatment group compared with the placebo
Furthermore, FOXO4-DRI targets the tumor suppressor p53, a crucial protein, which may lead to various side effects in clinical trials 37
Glutathione works on the environment
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Z Pflanzenphysiol 95:7785, 1979
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