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The most common are digestive symptoms, including nausea, vomiting, diarrhoea, constipation and abdominal discomfort, which are usually mild to moderate and often improve as your body adjusts, particularly when doses are increased gradually

10.1016/j.jep.2018.09.002 105 WangQ

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5.5 Severe Gastrointestinal Adverse Reactions DOCVARIABLE vault_nd_fcd34bb4-3cb3-473c-864a-ed4ae529f642 \* MERGEFORMAT Use of GLP-1 receptor agonists, including BYDUREON BCISE, has been associated with gastrointestinal adverse reactions, sometimes severe [see Adverse Reactions (6)]