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NF-kB is activated in the epithelial cells and macrophages of emphysema patients, particularly during exacerbations [134]

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The condition has been associated with toxin exposure, chemotherapy, hepatitis, and rheumatoid arthritis (Kumar 2009b

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In contrast, novel additive including phosphate-adenine-glucose-guanosine-gluconate-mannitol (PAG3M), Erythro-Sol 5 (E-Sol5), and SOLX (AS-7) have pursued different strategies to allow RBC storage under alkaline conditions 32,33