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Cigna might require medical necessity evidence, while Blue Cross Blue Shield's coverage varies by location and plan specifics

In the SURMOUNT-5 trial (comparing tirzepatide to semaglutide at weight-loss doses), more people discontinued semaglutide due to side effects (5.6%) than tirzepatide (2.7%)

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Incomplete information spreads faster than nuanced explanations

The key indirect factors include: Reduced Appetite: Less chewing and smaller meal volumes reduce mechanical stimulation of saliva

Pregnancy and breastfeeding: Wegovy, and all GLP-1s are not safe in pregnancy or breastfeeding