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This study administered a culture of 13 common fecal bacteria via colon infusion, resulting in 70% of patients responding positively after four weeks

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One very important point: injectable B12 is primarily a medical treatment for a diagnosed deficiency

Zhu H, Naujokas MA, Park M

In a randomized, double-blind trial where women applied GHK-Cu encapsulated in a nano-lipid carrier twice daily for 8 weeks, the treatment group saw significant improvements in wrinkle depth and volume with no serious adverse events