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This is similar to results found in other GLP-1s, which also ultimately lead to a weight-loss plateau

These complications often lead to repeated doctor visits and, in some cases, hospital stays

The effects on kidney and CV events with finerenone treatment compared with placebo in the FIDELITY analysis were similar in 944 users of GLP-1RAs at baseline and in 12,082 nonusers of GLP-1RAs, with no significant interaction, thus supporting their combined use (24)

He says these are typically mild and temporary, and should not be overstated

Too much serotonin can lead to confusion, rapid heartbeat, vomiting, and, in some cases, be life-threatening

The FDA recommends discontinuing semaglutide at least 2 months before planned pregnancy due to its long washout period of approximately 5 weeks