Our findings of slightly elevated NF-B levels in the amniotic fluid of Down syndrome cases, although not reaching statistical significance, align with these experimental studies
It also feeds into the De Novo pPathway of NAD synthesis, making it an important player in the longevity conversation.* NMNH (Dihydro nicotinamide mononucleotide) is the reduced form of NMN and is metabolized through a separate pathway in the NAD metabolome
First, we fused the scFv to the C-terminus of FcRIIIa (v2)

Omega-3 Fatty Acids (EPA/DHA) Dose: 24 grams/day Why: Reduce neuroinflammation, promote repair of damaged neuronal membranes Clinical Note: Especially helpful for athletes or students recovering from sports-related concussion Creatine Monohydrate Dose: 1020 grams/day, split into 24 doses Why: Boosts brain energy and mitochondrial functionespecially important in the early stages of recovery Bonus: Also supports muscle recovery, making it useful for active individuals Magnesium Dose: ~400 mg/day Why: Supports neurotransmitter regulation and better sleep, both of which are critical during concussion recovery Pro Tip: Ask your physical therapist which form of magnesium is best for your symptoms Vitamin D Dose: 2,0005,000 IU/day Why: May support vestibular system and reduce long-term post-concussion symptoms Citicoline (Choline) Dose: 12 grams/day Why: Aids in brain cell membrane repair and memory function Other Nutrients That May Help With Concussion Recovery Vitamin E Protects brain cells from oxidative stress Riboflavin (B2) May reduce headache frequency N-Acetylcysteine (NAC) Supports glutathione, your brains primary antioxidant Wild Blueberry Extract Improves cognitive function and memory Boswellia Serrata Anti-inflammatory plant compound BCAAs May help balance excitatory and inhibitory neurotransmitters after concussion Our Columbia-Based Approach to Concussion Recovery Concussion recovery isnt one-size-fits-all

Frequently Asked Questions Can you take Vitamin B complex injections without a diagnosed deficiency
Based on preclinical (animal and cellular) data only, inhibition of NNMT by 5-Amino-1MQ is theorised to: Raise intracellular NAD+ levels Activate SIRT1 and other sirtuins (proteins linked to metabolic regulation) Reduce fat cell (adipocyte) size and proliferation Improve insulin sensitivity These effects have been demonstrated in mouse models (Neelakantan et al., 2019), but robust human clinical trial data are currently absent