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Each increase may temporarily intensify side effects before tolerance develops again

Now, there are deadlines for pharmacies and outsourcing facilities in April and May, respectively, to cease production, while the provided off-ramp gives patients and providers time for medication transition

10.1021/acsnano.3c04462 125 YerraV

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Funding This work was supported by grants from the National Natural Science Foundation of China (81971933, 81770592, and 81671570), National Science and Technology Major Project of China (2017ZX10202202-004 and 2018ZX10301202)