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Moreover, chromatin immunoprecipitation (ChIP)qPCR analysis further validated the binding capacity of E2F1 on gpx4 in control activated CD8 + T cells rather than GPX4 cKO cells (Figure 6I)

[DOI] [PubMed] [Google Scholar] 122.Wang Y, et al

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Acetylation promotes BCAT2 degradation to suppress BCAA catabolism and pancreatic cancer growth

SMARCA4- , SMARCB1- and PBRM1-deficient cancer cells have low basal levels of GSH due to attenuated expression of SLC7A11 SLC7A11 Previously, we showed that ARID1A deficiency attenuated transcriptional expression of SLC7A11 , leading to low basal levels of GSH