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It works by inhibiting NNMT, which may affect cellular energy metabolism and fat storage pathways

Prepubertal cryptorchidism not due to anatomical obstruction: Selected cases of hypogonadotropic hypogonadism in males: NOTE: Prior to diluting NOVAREL with Bacteriostatic Water for Injection (Table 1): Induction of ovulation and pregnancy in the anovulatory, infertile woman in whom the cause of anovulation is secondary and not due to primary ovarian failure and who has been appropriately pretreated with human menotropins (See prescribing information for menotropins for dosage and administration for that drug product)

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18-24 months: Approaching labeled expiration