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doi: 10.1016/j.intimp.2019.106112 217 ZhangMZhaoFGuoMDuanMXieYQiuL

The process works for most people, but not all

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Inadequate secretion of intrinsic factor, resulting from lesions that destroy the gastric mucosa (ingestion of corrosives, extensive neoplasia), and a number of conditions associated with a variable degree of gastric atrophy (such as multiple sclerosis, certain endocrine disorders, iron deficiency, and subtotal gastrectomy)

The 75/25 ratio places tirzepatide in the same category as well-designed exercise and nutrition programs and surgical interventions

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