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The NAD + /NADH redox pair modulates gene expression through redox-sensitive transcription factors [9], acts as a precursor of multiple NAD + -dependent enzymes involved in synaptic plasticity and neuronal stress resistance, and regulates crucial signaling pathways related to neuronal survival [10]

The only way to change concentration is with a new, unreconstituted vial

10.1146/annurev-physiol-020518-114742 491 WelchJ