In myoblast culture models, researchers observed that IGF-1 LR3 is associated with increased myotube formation, protein synthesis rates, and satellite cell activation markers
Both can support fat metabolism, better sleep, and healthier aging
However, the therapy at this dosage also led to a high incidence of side effects such as joint pain (50% of patients) and swelling in the limbs (37% of patients) [13]
Anti-aging: Some studies suggest that higher levels of IGF-1 are associated with greater muscle mass and improved physical capacity, which is why its often researched in the context of aging
Bottom line: A higher dose of a poorly absorbed supplement is often less effective than a moderate dose of a highly bioavailable liposomal formula
Studies designed to isolate IGF1R-specific effects sometimes employ selective IGF1R antagonists alongside LR3 to control for this hybrid activity