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Like albiglutide, it has a lower probability of hypoglycemia and no significant weight loss

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Accordingly, hyperfiltration decreases according to tubular glomerular feedback due to increased Na in the distal tubule

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TRPV1 activation promotes the influx of calcium as a second messenger for the induction of pro-inflammatory cytokines and chemokines

Through these diverse metabolic pathways, astrocytes serve as indispensable metabolic supporters of neurons, ensuring energy balance, neurotransmitter recycling and neuroprotection within the CNS