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Invest Ophthalmol Vis Sci 55(12):81739 Thaller M et al (2023) The idiopathic intracranial hypertension prospective cohort study: evaluation of prognostic factors and outcomes

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This binding triggers a cascade of effects: delayed gastric emptying, reduced glucagon secretion, enhanced insulin sensitivity, and most importantly for weight loss, decreased food intake through central appetite suppression (Wilding et al., NEJM, 2021)

P-rank scores show that GLP-1RA were ranked first in reducing the risk of MACE (88.8%) while SGLT-2 inhibitors were ranked second (77.5%) (Table S2)

Moreover, cages were renewed more frequent than usual to avoid coprophagia, as it could be an additional source of B12

Thus, they may be unreliable when it comes to avoiding vitamin B12 deficiency