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DYRK1A inhibition and cognitive rescue in a Down syndrome mouse model are induced by new fluoro-DANDY derivatives

Multiple sclerosis, characterized by multiple demyelinating lesions of the spinal cord and brain, has a progressive neurodegenerative pattern (Manu et al., 2021

Pregnancy and breastfeeding represent absolute contraindications requiring immediate discontinuation regardless of dose

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All work is non-clinical and mechanistic in nature