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Ipamorelin was optimized for GHSR-1a selectivity, which is the structural basis for its differentiated hormonal profile
However, the timing of supplementation is critical to maximizing its benefits
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All use is strictly in vitro and for research purposes only
Ipamorelin is also selected because it does not significantly raise cortisol or other pituitary hormones at effective GH-releasing doses, a selectivity advantage over older GHRPs like GHRP-6
These findings suggest that the observed BMC increase might potentially be attributed to improved bone size and structure, while the volumetric BMD possibly remained the same
