Enzyme inducers such as phenytoin, carbamazepine, and rifampin accelerate hepatic T3 clearance, whereas estrogen therapy and some protease inhibitors increase thyroxine-binding globulin, indirectly altering free T3 fractions
Incretin mimetics have demonstrated safety and efficacy in advanced kidney disease, however multiple studies have shown that use of GLP1-RA have shown improvements in glycemic control, body weight reductions, improved beta cell function, and decreased incidence hypoglycemia as compared to DPP4i in a general diabetes population 26,27,28,29,30,31 , effects which might explain the reduction of acute healthcare utilization observed in this study of patients with CKD treated with GLP1-RA as compared to DPP4i
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J Pharm Sci, 2011
Its inclusion reflects its standing in the industry, though it sits outside the reach of typical research procurement
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