doi: 10.1038/d41573-023-00185-8 Summary Keywords rheumatoid arthritis, cGAS, STING, signaling pathway, treatments Citation Zhu Q and Zhou H (2024) The role of cGAS-STING signaling in rheumatoid arthritis: from pathogenesis to therapeutic targets
GLP-1 receptor agonists, including semaglutide (Ozempic/Wegovy) and tirzepatide (Mounjaro), mimic a natural hormone called GLP-1
"Delta-sleep-inducing peptide (DSIP): an update." Peptides
Key points Obesity is a risk factor for developing osteoarthritis (OA), gout, rheumatoid arthritis (RA), psoriatic arthritis (PsA) and axial spondyloarthritis (axSpA), and is associated with higher disease activity and/or severity, and worse response to common treatments
Choose a Bioavailable Form: Opt for a liposomal liquid rather than a standard capsule
What Id genuinely like to see, and what the field needs, is a properly conducted Phase III randomised controlled trial in fibromyalgia patients, ideally with a sub-group of people with hypermobility and EDS, using low to moderate doses and with muscle mass, GI function, and bone health as pre-specified safety endpoints
