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Meng J, Li Y, Sun F, et al (2024) Salidroside alleviates LPS-induced liver injury and inflammation through SIRT1- NF-B pathway and NLRP3 inflammasome

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Collectively, multifunctional metabolic enzymes act as pivotal hubs linking metabolic reprogramming to therapeutic resistance, serving as upstream initiators of signaling cascades that drive drug tolerance in CRC