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Trial Populations vs

Table 2B shows the annual eGFR decline (mL/min/1.73 m 2 /year) was 2.6 9.9 in monotherapy with a period of 28.0 19.6 months and 1.2 6.0 in combination therapy with a period of 33.8 17.1 months

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If you experience any suspected side effects from medications, report them through the MHRA Yellow Card Scheme (yellowcard.mhra.gov.uk or via the Yellow Card app)

Activation of PPAR induces the transcription of a range of genes related to FAO in the mitochondria, peroxisomes, and cytochromes, thereby reducing hepatic lipid levels [77, 80, 81, 83]