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Trial populations and endpoints vary across studies, and individual outcomes vary

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Long-chain fatty acids require an intracellular taxi to enter the mitochondria where they can be oxidized (burned) for energy (ATP) production

Proglucagon is subsequently processed by the prohormone convertases 1, 2 and 3 50 to produce, among other products, the 29-amino-acid-long GCG (in human, positions 5381, PSCK2) and the 30-amino-acid-long GLP-1 736 (positions 98127, PSCK1), which are the focus of this work