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While rare, Semaglutide can cause allergic reactions

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Each step roughly doubles the dose, placing significant new demands on the body systems affected by GLP-1 receptor activation

[4] [5] Semaglutide works by mimicking the incretin hormone GLP-1, which stimulates insulin secretion in a glucose-dependent manner, suppresses glucagon release, slows gastric emptying, and reduces appetite through central nervous system pathways

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