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Being aware of these effects and knowing how to manage them can improve treatment outcomes and comfort

13 Additionally, lactylation of TFEB at lysine 91 in tissues of PDA patients prevents its interaction with the E3 ubiquitin ligase WWP2, reducing TFEB ubiquitination and degradation, and thereby increasing its activity and autophagy flux, contributing to pancreatic cancer

Analyses were performed using Statistica 8.0 (StatSoft, Tulsa, OK) software (alpha = 5%)

This could be explained by the fact that the level of mitophagy in the skeletal muscle cells decreases with age, which, in turn, results in the decrease of energy supply in the muscles [12]

These studies would help identify potential pathways and biomarkers critical to improving early detection and therapeutic strategies for preeclampsia

Gene silencing was verified by detecting proteins via immunoblotting analysis after transient transfection with siRNA