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Several mechanisms have been postulated for elevation in heart rate with GLP-1 RAs, such as reflex tachycardia, increase in sympathetic nervous system activity and direct sino-atrial node action but none have been clinically proven yet [39]
Subsequently, 60 l of the VLDL-containing fraction were used for lipid extraction and shotgun analysis as previously described 93,94
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They found that people taking semaglutide (Ozempic) or tirzepatide versions of GLP-1 drugs were twice as likely to develop NAION (non-arteritic anterior ischemic optic neuropathy)
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