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The studys results provide insights into some known and previously unrecognized benefits and risks of GLP-1RA that may be useful to inform clinical care and guide research agendas. Potential Downsides to GLP-1s Al-Aly emphasizes that his study also highlighted potential downsides to the medications, including an increased risk of gastrointestinal problems such as nausea, vomiting, diarrhea, and in rare cases paralysis of the stomach

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It regulates autophagy through cellular recycling mechanisms, enhancing autophagic flux through adenosine monophosphate-activated protein kinase (AMPK) activation and mammalian target of rapamycin (mTOR) inhibition

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