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101 In rats with tail or foot amputation, and heparin, warfarin and aspirin application, without 62 or with nitric oxide (NO)-agents, NO synthase (NOS)-blocker N-nitro-L-arginine methyl ester (L-NAME) or NOS-substrate L-arginine, 63 prolonged bleeding and thrombocytopenia were counteracted

Apply gentle pressure with a clean gauze pad if needed, but do not rub the area

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Individual responses, safety profiles and pharmacokinetic parameters can vary significantly between species and between in vitro and in vivo models

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Almost certainly not