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Graham IM, Daly LE, Refsum HM, Robinson K, Brattstrm LE, Ueland PM, Palma-Reis RJ, Boers GHJ, Sheahan RG, Israelsson B, Uiterwaal CS, Meleady R, McMaster D, Verhoef P, Witteman J, Rubba P, Bellet H, Wautrecht JC, De Valk HW, Lis ACS, Parrot-Roulaud FM, Tan KS, Higgins I, and Garcon D (1997)

CagriSema: Fixed-ratio combination of two separate molecules -- cagrilintide (long- acting amylin analog) and semaglutide (GLP-1 agonist) -- co-administered in a single weekly injection

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Given the positive FRET signal observed when both NSD2 PWWP1 and UNC7096 are present, we used this setup to evaluate the displacement of UNC7096 by UNC10088 in the presence or absence of the FBXO22 FIST domain (Supplementary Fig